Nuklida · radioaktif
Bismut-213 (²¹³Bi)
Bismut-213 (²¹³Bi) adalah isotop radioaktif bismut dengan 83 proton dan 130 neutron (nomor massa 213). Waktu paruhnya 45,6 menit (± 0,04 menit), meluruh terutama lewat peluruhan beta minus (β⁻).
Data nuklida
- Unsur
- Bismut (Bi, Z = 83)
- Nomor massa (A)
- 213
- Proton (Z)
- 83
- Neutron (N)
- 130
- Massa atom
- 212.994383570 ± 0.000005455 u
- Waktu paruh
- 45,6 menit (± 0,04 menit)
- Mode peluruhan
- Peluruhan beta minus (β⁻) ( 97,91 %), Peluruhan alfa (α) ( 2,09 %)
- Inti anak
- Polonium-213 (²¹³Po), Talium-209 (²⁰⁹Tl)
- Tahun penemuan
- 1947
- Sumber data
- IAEA Atomic Mass Data Center (NUBASE) and IUPAC CIAAW, via PubChem
Kegunaan isotop bismut
- 212Bi and 213Bi (with half-lives of 1 h and 0.76 h, respectively) are both used in medicine for radioimmunotherapy as bismuth-labeled monoclonal antibodies to treat cancer cells from melanoma (skin cancer) (Fig. IUPAC.83.1) and ovarian cancer. Figure 4.83.2 compares the biologic effect of 131I and 213Bi using a specific monoclonal antibody, B-B4, coupled to 213Bi by a chelating agent (a substance that can form multiple bonds to a single metal ion). 213Bi is a mixed alpha and beta emitter with a half-life of 0.76 h. The primary mode of decay is by beta emission to the very short-lived alpha emitter 213Po. The 8.4 MeV alpha particle emitted by 213Po has a path length of 76 μm in human tissue and is responsible for its cytotoxic effects (toxic to living cells). 213Bi is produced from a series of alpha particle decays beginning with 225Ac, which is a pure alpha emitter with a half-life of 10 days. A schematic of the Institute for Transuranium Elements (ITU) Standard 225Ac/ 213Bi Radionuclide Generator is shown in Fig. IUPAC.83.3. 212Bi has been used for radioimmunotherapy of leukemia and for targeting the vascular endothelial cells (thin layer of simple squamous cells that forms the interface between circulating blood or lymph and the remainder of the vessel wall) of tumors.
Isotop bismut lainnya
¹⁸⁴Bi, ¹⁸⁵Bi, ¹⁸⁶Bi, ¹⁸⁷Bi, ¹⁸⁸Bi, ¹⁸⁹Bi, ¹⁹⁰Bi, ¹⁹¹Bi, ¹⁹²Bi, ¹⁹³Bi, ¹⁹⁴Bi, ¹⁹⁵Bi, ¹⁹⁶Bi, ¹⁹⁷Bi, ¹⁹⁸Bi, ¹⁹⁹Bi, ²⁰⁰Bi, ²⁰¹Bi, ²⁰²Bi, ²⁰³Bi, ²⁰⁴Bi, ²⁰⁵Bi, ²⁰⁶Bi, ²⁰⁷Bi, ²⁰⁸Bi, ²⁰⁹Bi, ²¹⁰Bi, ²¹¹Bi, ²¹²Bi, ²¹⁴Bi, ²¹⁵Bi, ²¹⁶Bi, ²¹⁷Bi, ²¹⁸Bi, ²¹⁹Bi, ²²⁰Bi, ²²¹Bi, ²²²Bi, ²²³Bi, ²²⁴Bi