Nuklida · stabil · alami

Praseodimium-141 (¹⁴¹Pr)

Praseodimium-141 (¹⁴¹Pr) adalah isotop stabil praseodimium dengan 59 proton dan 82 neutron (nomor massa 141). Kelimpahan alaminya 1.

Data nuklida

Unsur: Praseodimium (Pr, Z = 59)
Nomor massa (A): 141
Proton (Z): 59
Neutron (N): 82
Massa atom: 140.907659604 ± 0.000001607 u
Waktu paruh: Stabil
Mode peluruhan: Tidak meluruh
Kelimpahan alami: 1
Tahun penemuan: 1924
Sumber data: IAEA Atomic Mass Data Center (NUBASE) and IUPAC CIAAW, via PubChem

Because of its relatively short half-life (19.12 h) and decay primarily by beta decay (96.3 percent beta decay and 3.7 percent alpha decay), 142Pr has been proposed for two main innovative applications in medicine, namely in microsphere brachytherapy and in eye plaque brachytherapy. 142Pr is advantageous because penetration of the beta fraction of the radiation is limited to a few millimeters in tissue, therefore limiting the dose of radiation to the treated site. 142Pr may be produced either by fast neutron activation or thermal neutron activation of stable 141Pr. Research in metal-bearing radiopharmaceuticals is being conducted to determine the most efficient way to produce and process radioactive metals for in vivo tracing. This research has led to the development of a potential radionuclide generator that administers radioactive metal complexes to be observed during positron emission tomography (PET) imaging. A n(140Nd)/n(140Pr) amount-ratio radionuclide generator has been designed to administer 140Pr complexes, such as 140Pr-DTPA, to be used as a tracer during a PET scan. The half-life of 140Pr is 3.4 min. The n(140Nd)/n(140Pr) ratio radionuclide generators can also be used for administering 140Pr-phosphonate complexes to identify the development of skeletal metastases. Once the skeletal metastases are found, 153Sm-EDTMP can be administered as a radiotherapeutic agent to treat bone cancer (Fig. IUPAC.59.1). The half-life of 153Sm is 1.9 days.