Nuklida · radioaktif
Holmium-166 (¹⁶⁶Ho)
Holmium-166 (¹⁶⁶Ho) adalah isotop radioaktif holmium dengan 67 proton dan 99 neutron (nomor massa 166). Waktu paruhnya 26,812 jam (± 0,007 jam), meluruh terutama lewat peluruhan beta minus (β⁻).
Data nuklida
- Unsur
- Holmium (Ho, Z = 67)
- Nomor massa (A)
- 166
- Proton (Z)
- 67
- Neutron (N)
- 99
- Massa atom
- 165.932291209 ± 0.000000844 u
- Waktu paruh
- 26,812 jam (± 0,007 jam)
- Mode peluruhan
- Peluruhan beta minus (β⁻) ( 100 %)
- Inti anak
- Erbium-166 (¹⁶⁶Er)
- Tahun penemuan
- 1936
- Sumber data
- IAEA Atomic Mass Data Center (NUBASE) and IUPAC CIAAW, via PubChem
Kegunaan isotop holmium
- Radiosynovectomy with 166Ho-radiopharmaceutical agents can be used for treatment of arthritis. The half-life of 166Ho is 1.1 days. 166Ho ferric hydroxide macroaggregate ([ 166Ho] FHMA) radiosynovectomy is being used because FHMA minimizes extra-articular (outside a joint) leakage of the radioisotope,. 166Ho has been used for radioimmunotherapy (RIT) with labeled antibodies. The 166Ho-chitosan complex (a linear polysaccharide, which is a long-chain molecule like cellulose that is used by the body for energy storage) is being used for hepatic (liver) cancer therapy. 166Ho-labeled radiopharmaceuticals have been used for alleviating pain from bone metastases,,. 166Ho microspheres have been used for intra-arterial radioembolization (treatment where radioactive particles are delivered to a tumor through the bloodstream) of liver metastases (Fig. IUPAC.67.1). 166Ho is paramagnetic and emits both beta and gamma radiation, which makes it ideal for radioembolization. These properties also enable the distribution of 166Ho microspheres to be visualized with magnetic resonance imaging and single-photon emission computed tomography (SPECT). The 166Ho-Patch is a specially designed radioactive skin patch that is used for external radiation of superficial skin cancers and Bowen’s disease in areas that are sensitive and difficult to treat by methods that are more destructive and have poor cosmetic results (i.e. areas of the face),.
Isotop holmium lainnya
¹⁴⁰Ho, ¹⁴¹Ho, ¹⁴²Ho, ¹⁴³Ho, ¹⁴⁴Ho, ¹⁴⁵Ho, ¹⁴⁶Ho, ¹⁴⁷Ho, ¹⁴⁸Ho, ¹⁴⁹Ho, ¹⁵⁰Ho, ¹⁵¹Ho, ¹⁵²Ho, ¹⁵³Ho, ¹⁵⁴Ho, ¹⁵⁵Ho, ¹⁵⁶Ho, ¹⁵⁷Ho, ¹⁵⁸Ho, ¹⁵⁹Ho, ¹⁶⁰Ho, ¹⁶¹Ho, ¹⁶²Ho, ¹⁶³Ho, ¹⁶⁴Ho, ¹⁶⁵Ho, ¹⁶⁷Ho, ¹⁶⁸Ho, ¹⁶⁹Ho, ¹⁷⁰Ho, ¹⁷¹Ho, ¹⁷²Ho, ¹⁷³Ho, ¹⁷⁴Ho, ¹⁷⁵Ho, ¹⁷⁶Ho, ¹⁷⁷Ho, ¹⁷⁸Ho