Nuklida · radioaktif
Erbium-169 (¹⁶⁹Er)
Erbium-169 (¹⁶⁹Er) adalah isotop radioaktif erbium dengan 68 proton dan 101 neutron (nomor massa 169). Waktu paruhnya 9,392 hari (± 0,018 hari), meluruh terutama lewat peluruhan beta minus (β⁻).
Data nuklida
- Unsur
- Erbium (Er, Z = 68)
- Nomor massa (A)
- 169
- Proton (Z)
- 68
- Neutron (N)
- 101
- Massa atom
- 168.934598444 ± 0.000000326 u
- Waktu paruh
- 9,392 hari (± 0,018 hari)
- Mode peluruhan
- Peluruhan beta minus (β⁻) ( 100 %)
- Inti anak
- Tulium-169 (¹⁶⁹Tm)
- Tahun penemuan
- 1956
- Sumber data
- IAEA Atomic Mass Data Center (NUBASE) and IUPAC CIAAW, via PubChem
Kegunaan isotop erbium
- 169Er (with a half-life of 9.4 days) is used in radiosynovectomy, which is a regularly practiced radiotherapy, on rheumatoid arthritis patients whose condition is resistant to standard methods of treatment (Fig. IUPAC.68.1). Rheumatoid arthritis is a chronic, inflammatory, autoimmune disease of the joint capsule (synovial sac), which is lined with a thin membrane called the synovium, of an individual’s moveable joints (synovial joints). In radiosynovectomy, the radiopharmaceutical called 169Er- citrate colloid, which contains colloidal particles that are labeled with β-emitting 169Er, is directly injected into the synovial cavity (the cavity between the bones in a moveable joint inside of the synovium) of the affected joint. These radioactive-colloid particles are then phagocytized (engulfed) by macrophage-like synoviocytes as well as other phagocytizing inflammatory cells in the patient’s synovium. Necrosis (tissue death) and the inhabitation of cell proliferation (increase in number of cells) result from the radiation of the synovium and therefore, temporarily halts synovitis (which is the condition of when the synovium thickens with inflammation) and improves synovial joint function,,,.
Isotop erbium lainnya
¹⁴²Er, ¹⁴³Er, ¹⁴⁴Er, ¹⁴⁵Er, ¹⁴⁶Er, ¹⁴⁷Er, ¹⁴⁸Er, ¹⁴⁹Er, ¹⁵⁰Er, ¹⁵¹Er, ¹⁵²Er, ¹⁵³Er, ¹⁵⁴Er, ¹⁵⁵Er, ¹⁵⁶Er, ¹⁵⁷Er, ¹⁵⁸Er, ¹⁵⁹Er, ¹⁶⁰Er, ¹⁶¹Er, ¹⁶²Er, ¹⁶³Er, ¹⁶⁴Er, ¹⁶⁵Er, ¹⁶⁶Er, ¹⁶⁷Er, ¹⁶⁸Er, ¹⁷⁰Er, ¹⁷¹Er, ¹⁷²Er, ¹⁷³Er, ¹⁷⁴Er, ¹⁷⁵Er, ¹⁷⁶Er, ¹⁷⁷Er, ¹⁷⁸Er, ¹⁷⁹Er, ¹⁸⁰Er