Nuklida · radioaktif
Arsen-72 (⁷²As)
Arsen-72 (⁷²As) adalah isotop radioaktif arsen dengan 33 proton dan 39 neutron (nomor massa 72). Waktu paruhnya 26 jam (± 0,1 jam), meluruh terutama lewat peluruhan beta plus (β⁺).
Data nuklida
- Unsur
- Arsen (As, Z = 33)
- Nomor massa (A)
- 72
- Proton (Z)
- 33
- Neutron (N)
- 39
- Massa atom
- 71.926752291 ± 0.000004383 u
- Waktu paruh
- 26 jam (± 0,1 jam)
- Mode peluruhan
- Peluruhan beta plus (β⁺) ( 100 %)
- Inti anak
- Germanium-72 (⁷²Ge)
- Tahun penemuan
- 1939
- Sumber data
- IAEA Atomic Mass Data Center (NUBASE) and IUPAC CIAAW, via PubChem
Kegunaan isotop arsen
- 72As (with a half-life of 26 h) and 74As are useful in molecular imaging because they are radioactive isotopes that emit positrons that can be designed to bind to monoclonal antibodies (moAb), which accumulate in tumors and then 72As- or 74As-labeled ligands will bind to the moAbs. Once the 72As- or 74As-labeled ligand binds to the moAb, positron emission tomography (PET) is used to visualize the exact location of the tumor. A specific example of using radiolabeled antibodies for better imaging of tumors is the combination of 74As with bavituximab, which is an antibody that binds strongly to unique lipids on the surface of tumors. When a thiol group is introduced to bavituximab, arsenic is able to bind covalently, creating a simple and elegant radio-label for targeting cancerous tumors.
Isotop arsen lainnya
⁶⁰As, ⁶¹As, ⁶²As, ⁶³As, ⁶⁴As, ⁶⁵As, ⁶⁶As, ⁶⁷As, ⁶⁸As, ⁶⁹As, ⁷⁰As, ⁷¹As, ⁷³As, ⁷⁴As, ⁷⁵As, ⁷⁶As, ⁷⁷As, ⁷⁸As, ⁷⁹As, ⁸⁰As, ⁸¹As, ⁸²As, ⁸³As, ⁸⁴As, ⁸⁵As, ⁸⁶As, ⁸⁷As, ⁸⁸As, ⁸⁹As, ⁹⁰As, ⁹¹As, ⁹²As